Bronchol Cough Syrup 200ml

 Bronchol Cough Syrup 200ml, a popular respiratory medication in Nigeria and other regions:

Bronchol Cough Syrup 200ml - Complete Formulation Profile

📌 Therapeutic Class:
Expectorant + Bronchodilator + Antitussive Combination

✅ Active Ingredients (per 5ml):

• Diphenhydramine HCl (12.5mg) - 1st-gen antihistamine with antitussive effects

• Ephedrine HCl (5mg) - Bronchodilator/decongestant

• Ammonium Chloride (80mg) - Expectorant

• Sodium Citrate (50mg) - Mucolytic agent

• Menthol (1.2mg) - Local soothing agent

🎯 Primary Clinical Indications:

• Productive cough with bronchospasm

• Allergic bronchitis

• Asthmatic cough variant

• Post-infectious cough

• Chronic bronchitis symptom management

💊 Dosage Schedule:

• Adults: 10ml (2 teaspoonfuls) 3-4 times daily

• Children 6-12 years: 5ml 3-4 times daily

• Maximum Duration: 7 days continuous use

• Administration Note: Take with warm water for enhanced expectoration

⚖️ Pharmacological Actions:

• Onset: 20-40 minutes (bronchodilator effect)

• Peak activity: 1-2 hours

• Duration: 4-6 hours per dose

⚠️ Absolute Contraindications:

• MAOI therapy (risk of hypertensive crisis)

• Severe hypertension

• Coronary artery disease

• Hyperthyroidism

• Prostatic hypertrophy with retention

🔄 Critical Drug Interactions:

• ↑ CNS depression with alcohol/sedatives

• ↑ Sympathomimetic effects with other stimulants

• ↓ Efficacy with urinary alkalinizers

• Dangerous with digitalis glycosides (arrhythmia risk)

📉 Adverse Effects:

• Common: Dry mouth, mild tremors, drowsiness

• Less common: Palpitations, urinary hesitancy

• Rare: Paradoxical bronchospasm, angle-closure glaucoma

🔬 Monitoring Parameters:

• Respiratory pattern

• Sputum characteristics

• Vital signs in elderly

• CNS status in children

💡 Essential Patient Advice:

• Avoid alcohol completely

• May impair alertness (caution when driving)

• Maintain good fluid intake

• Not for persistent dry cough

• Shake well before use

• Sugar content: ~3.5g per 10ml dose

🛒 Therapeutic Alternatives:

• For non-sedating option: Aerolin Expectorant

• Pure expectorant: Bisolvon Syrup

• Children's formula: Piriton Expectorant