Nurofen 24's

 Nurofen 24's, a popular NSAID medication:

Nurofen 24's (Ibuprofen) - Complete Drug Profile

📌 Therapeutic Class:
NSAID (Non-Steroidal Anti-Inflammatory Drug)

✅ Active Ingredient:

• Ibuprofen 200mg (standard strength) or 400mg (extra strength) per tablet

🎯 Primary Clinical Indications:
✔️ Mild-to-moderate pain (headache, dental pain, dysmenorrhea)
✔️ Inflammation (arthritis, soft tissue injuries)
✔️ Fever reduction (viral/bacterial infections)

💊 Dosage Guidelines:

• Adults & Children ≥12yrs:

  • 1-2 tablets (200mg) every 4-6h

  • Max daily dose: 6 tablets (1200mg)

• For 400mg tablets: 1 tablet every 6-8h (max 3 tablets/day)

• Take with food/water to reduce GI irritation

⚖️ Pharmacokinetics:

• Onset: 30-60 minutes

• Peak effect: 1-2 hours

• Duration: 4-6 hours

⚠️ Critical Contraindications:

• Active peptic ulcers/GI bleeding

• Severe heart/kidney/liver disease

• 3rd trimester pregnancy

• NSAID-induced asthma/urticaria

🔄 Key Drug Interactions:

• ↑ Bleeding risk with warfarin/SSRIs

• ↑ Nephrotoxicity with ACE inhibitors/diuretics

• ↓ Efficacy of antihypertensives

📉 Adverse Effects:

• Common: Heartburn, nausea

• Serious: GI ulcers, acute kidney injury

• Rare: Stevens-Johnson syndrome

💡 Patient Counseling:

• Do not exceed recommended dose

• Avoid alcohol (↑ GI bleeding risk)

• Stop use if black stools/vomiting blood occur

• Not for COVID-19 self-treatment

🛒 OTC Alternatives:

• Paracetamol (safer for stomach)

• Naproxen (longer duration)

📦 Pack Details:

• 24 coated tablets per pack

• Storage: Below 25°C

• Shelf-life: Typically 3 years

Note: Not recommended for children <12yrs (use pediatric suspensions). Discontinue after 3 days for fever or 10 days for pain unless medically advised. Higher 400mg/600mg doses require pharmacist consultation in some countries.