K-Fenak OTC 9s

K-Fenak OTC 9s (Ketoprofen) - Complete Drug Profile

📌 Therapeutic Class:
NSAID (Propionic Acid Derivative)

✅ Active Ingredient:

• Ketoprofen 12.5mg or 25mg (check pack strength)

• Note: Some formulations may contain additional ingredients

🎯 Primary Indications:
✔️ Mild-to-moderate pain (musculoskeletal, dental)
✔️ Inflammatory conditions (arthritis, tendinitis)
✔️ Dysmenorrhea
✔️ Post-traumatic swelling

💊 Dosage Guidelines (Adults ≥15yrs):

• 12.5mg: 1 tablet every 4-6 hours (max 6 tablets/24hrs)

• 25mg: 1 tablet every 8 hours (max 3 tablets/24hrs)

• Take with food to minimize GI irritation

⚖️ Pharmacokinetics:

• Onset: 30 minutes

• Peak effect: 1-2 hours

• Duration: 4-6 hours

• Half-life: 2-4 hours

⚠️ Critical Contraindications:

• Active peptic ulcer disease

• Severe renal/cardiac impairment

• Late pregnancy (3rd trimester)

• NSAID-induced asthma history

🔄 High-Risk Interactions:

• Warfarin (↑ bleeding risk)

• Diuretics (↓ efficacy + nephrotoxicity)

• Lithium (↑ toxicity risk)

• SSRIs (↑ GI bleeding)

📉 Adverse Effects:

• Common: Dyspepsia (15-20% incidence)

• Serious: GI ulceration (1-2% with chronic use)

• Rare: Stevens-Johnson syndrome

💡 Patient Counseling:

• Avoid alcohol completely

• Discontinue if black stools occur

• Not for self-medication >3 days for fever

• May cause dizziness (caution when driving)

🛒 OTC Alternatives:

• Ibuprofen (better GI tolerance)

• Diclofenac potassium (faster onset)