Ibugesic Plus 30s

 Ibugesic Plus 30s, a combination analgesic tablet:

Ibugesic Plus 30s - Complete Formulation Profile

📌 Therapeutic Class:
NSAID + Muscle Relaxant Combination

✅ Active Ingredients (per tablet):

• Ibuprofen (400mg) - NSAID (anti-inflammatory/analgesic)

• Paracetamol (325mg) - Analgesic/antipyretic

• Chlorzoxazone (250mg) - Muscle relaxant

🎯 Primary Clinical Indications:

• Musculoskeletal pain (backache, sprains)

• Post-traumatic inflammation

• Arthralgia/myalgia

• Dental pain with muscle spasm

• Tension headache with neck stiffness

💊 Dosage Guidelines:

• Adults: 1 tablet 2-3 times daily after meals

• Maximum: 3 tablets/24 hours

• Duration: Not to exceed 5 days without medical supervision

• Administration: Swallow whole with water

⚖️ Pharmacological Properties:

• Onset: 30-45 minutes (analgesia)

• Peak effect: 1-2 hours

• Duration: 4-6 hours

• Food delays absorption but reduces GI irritation

⚠️ Critical Contraindications:

• Peptic ulcer disease

• Severe hepatic/renal impairment

• Asthma/urticaria precipitated by NSAIDs

• Pregnancy (3rd trimester)

• Children below 12 years

🔄 Significant Drug Interactions:

• ↑ Bleeding risk with anticoagulants

• ↑ Lithium/MTX toxicity

• ↓ Efficacy of antihypertensives

• Additive sedation with CNS depressants

📉 Adverse Effects:

• Common: Drowsiness, dyspepsia

• Serious: GI bleeding, hepatotoxicity

• Rare: Stevens-Johnson syndrome

🔬 Monitoring Parameters:

• Liver enzymes (prolonged use)

• Renal function

• Signs of GI bleeding

• CNS depression

💡 Patient Counseling:

• Avoid alcohol completely

• Report any yellowing of eyes/skin

• Don't drive if drowsy

• Take after meals

• Don't combine with other NSAIDs

🛒 Therapeutic Alternatives:

• For pure analgesia: Paracetamol alone

• Non-sedating option: Diclofenac+Paracetamol

• Topical alternative: Diclofenac gel