Brufen 200 20s

Brufen 200 20s (Ibuprofen) – Complete Drug Profile

📌 Therapeutic Class:
NSAID (Non-Steroidal Anti-Inflammatory Drug)

✅ Active Ingredient:

• Ibuprofen 200mg per tablet

🎯 Primary Clinical Indications:
✔️ Mild-to-moderate pain (headache, dental pain, dysmenorrhea)
✔️ Inflammatory conditions (arthritis, tendinitis)
✔️ Fever reduction

💊 Dosage Guidelines:

• Adults & Children ≥12yrs:

  • 1–2 tablets every 4–6 hours

  • Max daily dose: 6 tablets (1200mg)

• Take with food/water to reduce GI irritation

⚖️ Pharmacokinetics:

• Onset: 30–60 minutes

• Peak effect: 1–2 hours

• Duration: 4–6 hours

• Half-life: ~2 hours

⚠️ Critical Contraindications:
❌ Active peptic ulcers/GI bleeding
❌ Severe heart/kidney/liver disease
❌ 3rd trimester pregnancy
❌ NSAID-induced asthma/urticaria

🔄 Key Drug Interactions:

• ↑ Bleeding risk with warfarin, SSRIs

• ↑ Nephrotoxicity with ACE inhibitors/diuretics

• ↓ Efficacy of antihypertensives

📉 Adverse Effects:

• Common: Dyspepsia, nausea

• Serious: GI ulcers, acute kidney injury (rare with short-term use)

• Rare: Severe skin reactions (SJS/TEN)

💡 Patient Counseling:
✔️ Do not exceed recommended dose
✔️ Avoid alcohol (↑ GI bleeding risk)
✔️ Stop use if black stools/vomiting blood occur
✔️ Not for long-term use without medical supervision

🛒 OTC Alternatives:

• Paracetamol (safer for stomach)

• Naproxen (longer duration)

📦 Pack Details:

• 20 tablets per pack

• Storage: Below 30°C

• Shelf-life: Typically 3 years

Note:

• Not for children <12yrs (use pediatric suspension).

• Discontinue after 3 days for fever or 10 days for pain unless advised otherwise.

• Higher doses (400–600mg) may require medical advice.

Regulatory Status:

• OTC in most countries (check local regulations).

• Prescription-only in some regions for higher strengths.

Clinical Tip:
For inflammatory pain, Brufen is more effective than paracetamol. For fever/mild pain, paracetamol is often preferred due to better GI safety.