Adco-Linctopent 200ml

Adco-Linctopent 200ml, a combination cough syrup available in South Africa and other regions:

Adco-Linctopent 200ml - Complete Formulation Profile

📌 Therapeutic Class:
Antitussive + Expectorant Combination

✅ Active Ingredients (per 5ml):

• Pentoxyverine Citrate (7.5mg) - Non-opioid cough suppressant

• Guaifenesin (50mg) - Expectorant

• Menthol (1mg) - Local soothing agent

🎯 Primary Clinical Indications:

• Dry, irritating cough

• Productive cough with difficulty expectorating

• Post-viral cough

• Bronchitis-associated cough

💊 Dosage Guidelines:

• Adults: 10ml every 4-6 hours (Max 40ml/24hrs)

• Children 6-12 years: 5ml every 6-8 hours (Max 20ml/24hrs)

• Not recommended for children under 6 years

• Best taken with warm water to enhance expectoration

⚖️ Pharmacological Properties:

• Onset: 20-30 minutes (cough suppression)

• Peak effect: 1-2 hours

• Duration: 4-6 hours

• Pentoxyverine has both central and peripheral antitussive action

⚠️ Critical Contraindications:

• Respiratory depression

• Myasthenia gravis

• Glaucoma

• Prostate enlargement with urinary retention

• Pregnancy (1st trimester)

🔄 Significant Drug Interactions:

• ↑ CNS depression with alcohol/sedatives

• ↑ Anticholinergic effects with TCAs/antipsychotics

• Possible interaction with MAOIs

• Reduced efficacy with cough preparations containing codeine

📉 Adverse Effects:

• Common: Mild drowsiness, dry mouth

• Less common: Blurred vision, nausea

• Rare: Urinary retention, constipation

🔬 Monitoring Parameters:

• Cough pattern changes

• Sputum characteristics

• Urinary function in elderly

• CNS effects in children

💡 Patient Counseling:

• May cause drowsiness (caution when driving)

• Maintain adequate hydration

• Not for persistent cough (>1 week)

• Sugar-free formulation (diabetic-friendly)

• Shake well before use

🛒 Therapeutic Alternatives:

• For pure suppression: Codeine linctus

• Non-drowsy option: Dextromethorphan syrups

• Pediatric formula: Simple Linctus Pediatric

📦 Product Specifications:

• 200ml bottle = 20 adult doses

• Storage: Below 25°C

• Shelf-life: Typically 2 years